Registered Nurse Salary in St. Louis, MO
Based on 2025 data from the U.S. Bureau of Labor Statistics
Salary Range in St. Louis
Registered Nurse Salary in Other Cities
How Much Does a Registered Nurse Make in St. Louis, MO?
The median Registered Nurse salary in St. Louis, MO is $88,800 per year as of 2025, according to the U.S. Bureau of Labor Statistics. This is 9% lower than the national median of $97,550.
Salaries in St. Louis range from $61,800 at the 10th percentile to $126,800 at the 90th percentile. The middle 50% of Registered Nurses in St. Louis earn between $73,000 and $108,200 per year.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025. Occupation: Registered Nurse (SOC 29-1141).
Frequently Asked Questions
How much does a Registered Nurse make in St. Louis, MO?
The median Registered Nurse salary in St. Louis, MO is $88,800 per year as of 2025, according to the U.S. Bureau of Labor Statistics.
What is the salary range for a Registered Nurse in St. Louis?
Registered Nurse salaries in St. Louis range from $61,800 at the 10th percentile to $126,800 at the 90th percentile. The middle 50% earn between $73,000 and $108,200 per year.
Is St. Louis a good place to work as a Registered Nurse?
St. Louis Registered Nurse salaries are 9% lower than the national median. St. Louis pays below the national average for this role.
Where does the salary data come from?
All data comes from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey — the most comprehensive salary database in the United States, covering approximately 830 occupations across 600+ metropolitan areas.