Nurse Practitioner Salary in St. Louis, MO
Based on 2025 data from the U.S. Bureau of Labor Statistics
Salary Range in St. Louis
Nurse Practitioner Salary in Other Cities
How Much Does a Nurse Practitioner Make in St. Louis, MO?
The median Nurse Practitioner salary in St. Louis, MO is $120,200 per year as of 2025, according to the U.S. Bureau of Labor Statistics. This is 9% lower than the national median of $132,300.
Salaries in St. Louis range from $82,600 at the 10th percentile to $164,000 at the 90th percentile. The middle 50% of Nurse Practitioners in St. Louis earn between $100,400 and $143,000 per year.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025. Occupation: Nurse Practitioner (SOC 29-1171).
Frequently Asked Questions
How much does a Nurse Practitioner make in St. Louis, MO?
The median Nurse Practitioner salary in St. Louis, MO is $120,200 per year as of 2025, according to the U.S. Bureau of Labor Statistics.
What is the salary range for a Nurse Practitioner in St. Louis?
Nurse Practitioner salaries in St. Louis range from $82,600 at the 10th percentile to $164,000 at the 90th percentile. The middle 50% earn between $100,400 and $143,000 per year.
Is St. Louis a good place to work as a Nurse Practitioner?
St. Louis Nurse Practitioner salaries are 9% lower than the national median. St. Louis pays below the national average for this role.
Where does the salary data come from?
All data comes from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey — the most comprehensive salary database in the United States, covering approximately 830 occupations across 600+ metropolitan areas.